APIC’s research archive

APIC has sponsored or supported the following studies, listed chronologically by end date:


Preventing Avoidable Infectious Complications by Adjusting Payment (PAICAP Project)
The goal of this study, conducted by Harvard Medical School and Harvard Pilgrim Health Care Institute, was to assess the impact of Medicare’s policy of adjusting payment for healthcare-associated infections (HAI) on health outcomes and costs in U.S. hospitals. Learn more.


Prevention of Nosocomial Infections and Cost Effectiveness (P-NICE)
The first phase of Columbia University School of Nursing’s three-year, two-phase study is titled Prevention of Nosocomial Infections and Cost Effectiveness Analysis (P-NICE). This phase described infection control department staffing and interventions implemented in 415 participating intensive care units across the U.S. The second phase (P-NICER) is currently underway. Learn more.

The Changing Role of the Infection Preventionist
The Columbia University School of Nursing team and APIC designed a two-year study to evaluate the effects of the California Healthcare-Associated Infection Prevention Initiative (CHAIPI) on infection control procedures, infection rates, and changes in the role of the infection preventionist. CHAIPI sought to reduce unnecessary morbidity, mortality, and costs associated with healthcare-associated infections in California hospitals. Learn more.


National U.S. Inpatient Healthcare Facility Clostridium difficile Survey
APIC conduced the largest, most comprehensive prevalence survey of C. difficile, which revealed that colonization and infection rates among hospitalized adults were much higher than previously estimated. Learn more.


Methicillin-Resistant Staphylococcus aureus (MRSA) Prevalence Study (MRSA I)
Infection preventionists at more than 1,200 U.S. hospitals provided prevalence data, demonstrating that healthcare-associated rates of MRSA were much higher than previously reported. This was the first major research study published by APIC. Learn more.