Clostridioides difficile

Often referred to as deadly diarrhea, Clostridioides difficile (C. diff) causes at least 250,000 infections and 14,000 deaths each year in hospitalized patients. People who are most at-risk for getting C. diff include older adults and patients who take antibiotics while receiving medical care. The antibiotics can kill the “good germs,” allowing C. diff to grow. This page contains C. diff prevention resources and education for both healthcare professionals and consumers.

The following links are APIC resources on Clostridium difficile prevention for healthcare professionals.

Implementation guides and tools

Education & training

APIC offers a comprehensive collection of clinical education and professional development programs. The following resources are educational opportunities related to Clostridium difficile. Visit the Education & Certification page for more educational opportunities.

Prevention Strategist articles

The following links include articles on Clostridium difficile from APIC’s Prevention Strategist magazine.

AJIC articles

Search the American Journal of Infection Control website for more articles on Clostridium difficile. To access these articles, you need to first login to the APIC website.

External resources

The following links are APIC and external resources on Clostridium difficile for consumers.


External resources