Compendium of Strategies to Prevent Healthcare-Associated Infections in Acute Care Hospitals

The Compendium is a set of strategies published by the Society for Healthcare Epidemiology of America and the Infectious Diseases Society of America in partnership with APIC, the American Hospital Association, and The Joint Commission. Originally published in 2008 and updated in 2014, this publication provides guidance on preventing six of the most common healthcare-associated infections: Clostridium difficile, methicillin-resistant Staphylococcus aureus, central line-associated bloodstream infections, ventilator-associated pneumonia, catheter-associated urinary tract infections, and surgical site infections. 

Access the 2014 Compendium update

Access the Spanish translation of the Compendium (2008 version).

Access the Portuguese translation of the Compendium
 (2008 version).

Rationale for hand hygiene recommendations after caring for a patient with Clostridium difficile infection

While soap and water have long been considered the preferred method of hand hygiene to remove C. difficile infection (CDI) spores following the care of CDI patients, no acute-care studies exist showing the same result cannot be achieved using alcohol-based hand hygiene products. For that reason, preferential use of soap and water following CDI patient care is not recommended during non-outbreak settings.


Access the Compendium patient education guides:

Surgical site infection (SSI)

Central line-associated bloodstream infection (CLABSI)

Catheter-associated urinary tract infection (CAUTI)

Ventilator-associated pneumonia (VAP)

Clostridium difficile

Methicillin-resistant Staphylococcus aureus (MRSA)

Vancomycin-resistant enterococcus (VRE)