The Centers for Disease Control and Prevention (CDC) awarded $26 million to support applied research at five academic medical centers as part of a patient safety effort known as Prevention Epicenters Program. Together with CDC, these Prevention Epicenters develop and test innovative approaches to preventing infections and improving patient safety in healthcare settings. The program was begun to address scientific questions regarding prevention of healthcare-associated infections, antibiotic resistance, microbiome health, and other adverse events. The new funding more than doubles previous awards and expands and extends the Prevention Epicenters program to 2020. Read about the Prevention Epicenters Program and the 2016 awardees.